Creatine is among the most well-researched and effective supplements. It can help with exercise performance by rapidly producing energy during activity. Creatine may also provide cognitive benefits. Creatine is a molecule produced in the body. It stores high-energy phosphate groups in the form of phosphocreatine. Phosphocreatine releases energy to aid cellular function during stress. This effect causes strength increases after creatine supplementation, and can also benefit the brain, bones, muscles, and liver. Most of the benefits of creatine are a result of this mechanism.
Creatine monohydrate can be supplemented through a loading protocol. To start loading, take 0.3 grams per kilogram of bodyweight per day for 5–7 days, then follow with at least 0.03 g/kg/- day either for three weeks (if cycling) or indefinitely (without additional loading phases).